🚀 Mission Context
The Artemis-2 mission, scheduled for September 2025, will be historic for several reasons:
- First crewed flight around the Moon since 1972 (after Apollo 17).
- First manned test of the SLS rocket + Orion capsule combination.
- Crew of four astronauts — including the first Canadian and the first woman to fly to the Moon.
- Duration: ~10 days, with about 6 days in deep space, including a lunar flyby at a distance of up to 8,889 km behind its far side.
But beyond engineering tasks — testing life support systems, navigation, communications — the main "scientific payload" will be the astronauts themselves.
🧪 Biomedical Experiments: What Will Be Studied?
Unlike the ISS, where conditions are microgravity + Earth's magnetosphere protection, Artemis-2 will take humans into deep space, where:
- Gravity changes (from 1g at launch → 0g in flight → brief overloads during maneuvers).
- Radiation levels are 100–300 times higher than on Earth, and 2–3 times higher than on the ISS.
- Psychological pressure — isolation, remoteness from Earth, no possibility of rapid evacuation.
- Circadian rhythms — disrupted due to the absence of the usual "day/night" cycle.
NASA will focus on three key aspects:
1. 🧬 Impact of Space Radiation on the Body
- Dosimeters installed inside spacesuits and the capsule.
- Analysis of biomarkers in blood and urine before, during, and after the flight — for DNA damage, oxidative stress, inflammatory reactions.
- Special attention to cognitive functions: daily tests on memory, attention, reaction speed.
Goal: Understand the risks for future Mars missions, where radiation exposure is even higher.
2. 😴 Sleep and Circadian Rhythms in Deep Space
- Astronauts will wear actigraphs — devices that track sleep-wake cycles.
- The Orion cabin features adjustable LED lighting, simulating Earth's cycle (blue light in the morning → warm in the evening).
- Diaries of subjective well-being and fatigue are kept.
Problem: In space, without natural light and gravity, the brain loses "anchors" for biorhythms. This leads to insomnia, decreased concentration — critical for mission safety.
3. 😰 Psychological Stress and Group Dynamics
- The crew undergoes daily psychological surveys.
- Cameras and microphones (with crew consent) are used to analyze communication, voice tone, non-verbal signals.
- Testing mental health support tools: VR relaxation, family communication, "smart" interfaces to reduce cognitive load.
Note: The Artemis-2 mission is a rehearsal for Artemis-3 (Moon landing) and beyond — for Mars. It is crucial to understand how people behave in isolation, 400,000 km from Earth, without the "safety net" of the ISS.
🌍 Why Is This Important?
Since 1972, no human has ventured beyond Earth's magnetosphere. All data on the effects of deep space on humans is theoretical or obtained from animals/ground simulators.
Artemis-2 is the first live human experiment in real interplanetary space conditions.
This data will:
- Help design radiation protection systems for future lunar bases and Martian ships.
- Allow optimization of sleep and rest regimes for long-duration missions.
- Provide the key to maintaining mental health in isolation — critical for expeditions to Mars (2–3 years!).
👨🚀 The Crew — Not Just Pilots, but "Living Laboratories"
The astronauts:
Reid Wiseman
Commander, USA
Victor Glover
Pilot, USA — first African American on a lunar mission
Christina Koch
Mission Specialist, USA — first woman in lunar orbit
Jeremy Hansen
Mission Specialist, Canada — first Canadian beyond the ISS
They are not just "flying around the Moon." They are the first volunteers of a new era in space medicine.
🔬 Connection to the ISS — But With a New Level of Complexity
Yes, the effects of microgravity have been studied on the ISS for decades: muscle atrophy, bone mass loss, changes in the cardiovascular system. But in deep space, two new factors are added:
- Galactic cosmic ray (GCR) radiation — high-energy particles that penetrate even through the spacecraft's hull and damage cells.
- Lack of "psychological proximity" to Earth — from the ISS, you can see your home continent. From lunar orbit, Earth is a small ball. This is a powerful psychological trigger.
📆 What's Next?
Data from Artemis-2 will be immediately integrated into preparations for:
- Artemis-3 (2026–2027) — landing near the Moon's south pole.
- Lunar Gateway station — a permanent "point" in deep space.
- Mars missions — planned for the 2030s.
🌌 Conclusion: Humans as Explorers — and as Subjects of Study
Artemis-2 is not just a "flight around the Moon." It is humanity's return to deep space — and the first step toward understanding how to survive there long-term.
The astronauts on this mission are heroes not only of engineering, but of science. They risk not only their lives, but their health — so that future generations can live and work beyond Earth.
They are not just flying to the Moon.
They are flying beyond the known — and bringing science with them to light the way for all of us.